A suspected drunk driver led law enforcement on a high speed chase from Republic to the Webster/Laclede County Line.
Republic Police had a report of a suspected D-U-I driver.
They stopped the 39 year old driver at the Brookline Church of Christ, but he drove off.
The car rammed a Republic police car on State Highway 174.
Greene County Deputies picked up the chase after the driver got on to the Interstate.
The driver struck a Greene County patrol car and several other drivers before crashing into a guardrail between Marshfield and Conway.
The suspect was taken into custody.
The City of Republic says charges are pending.
None of the officers or civilian drivers were injured.